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Federal (FBISE) · FBISE HSSC-II science paper · Free

2nd Year Biology Board Pattern Paper 2026

85 marks · 3 hours (Section A: 25 minutes) · 40 questions. Covers: 15 chapters (01. Digestive System of Man to 15. Pharmacological Drugs).

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2nd Year Biology Board Pattern Paper 2026

2nd Year · Biology · Federal (FBISE)

Name: ____________Roll No: ________Class/Section: ________Date: ________Total marks: 85Time: 3 hours (Section A: 25 minutes)

Q1. Multiple choice questions (Attempt all · 17 × 1 = 17)

  1. Steroid hormones are secreted by
    1. the adrenal cortex
    2. the gonads
    3. the thyroid
    4. both A and B
  2. Which of the following is the respiratory surface in human respiratory system?
    1. larynx
    2. trachea
    3. bronchi
    4. alveoli
  3. Which structure prevents food from entering the trachea during swallowing?
    1. Epiglottis
    2. Soft palate
    3. Tongue
    4. Uvula
  4. Which type of antibiotic inhibits bacterial cell wall synthesis?
    1. Tetracyclines
    2. Penicillins
    3. Sulfonamides
    4. Fluoroquinolones
  5. Which scientific field studies the complete set of DNA of an organism, including all of its genes?
    1. Proteomics
    2. Transcriptomics
    3. Genomics
    4. Metabolomics
  6. Birds and mammals are classified as:
    1. Poikilotherms
    2. Homeotherms
    3. Ectotherms
    4. Amphibians
  7. Biotechnology can be defined as the use of:
    1. Metals
    2. Microorganisms
    3. Animals
    4. Air
  8. The two types of homology discussed in this section are:
    1. Genetic and metabolic homology
    2. Sequence and structure homology
    3. Plant and animal homology
    4. Behavioral and ecological homology
  9. Which human activity leads to enhanced greenhouse effect?
    1. Transportation and burning fossil fuels
    2. Photosynthesis in plants
    3. Recycling of waste
    4. Planting trees
  10. The heart is stopped during open heart surgery to:
    1. Reduce blood sugar
    2. Keep lungs functioning
    3. Remove cholesterol
    4. Allow repair of heart muscle
  11. Which enzyme in sweat helps to break down bacterial cell walls?
    1. Amylase
    2. Lysozyme
    3. Pepsin
    4. Lipase
  12. If the number of values is even, median is:
    1. The middle value
    2. Average of two middle values
    3. First value
    4. Last value
  13. What percent of nephron enters medulla?
    1. nephron loop
    2. proximal convoluted tubule
    3. distal convoluted tubule
    4. papillary duct
  14. In the reflex arc, effectors are usually:
    1. Dendrites
    2. Sensory receptors
    3. Muscles or glands
    4. Axons
  15. Which structure does not change its length during contraction?
    1. A band
    2. I band
    3. H zone
    4. Sarcomere
  16. Hyperthyroidism may cause:
    1. Graves’ disease
    2. Diabetes mellitus
    3. Goiter
    4. Dwarfism
  17. The respiration process at the cellular level is also called:
    1. External respiration
    2. Inhalation
    3. Internal respiration
    4. Exhalation

Q2. Short questions (Attempt any 7 of 10 · 7 × 3 = 21)

  1. How does CT scan work?
  2. What organs constitute the respiratory system?
  3. Name three main nitrogenous excretory products.
  4. What is a bony callus?
  5. Define or describe very briefly the following: "vasoconstriction"
  6. Define diastolic pressure.
  7. What is diabetes mellitus?
  8. Name the inactive forms of proteolytic enzymes secreted by the pancreas.
  9. Write the difference between white matter and grey matter
  10. What is the role of the expiratory centre?

Q3. Short questions (Attempt any 7 of 10 · 7 × 3 = 21)

  1. Why does each antibody bind only to a specific antigen?
  2. Differentiate between cloning vectors and expression vectors.
  3. What are the demerits of relying on range to decide future plans in scientific experiments?
  4. Mention two goals of using biological agents in warfare.
  5. What role does structural biology play in advancing biotechnology?
  6. Define climate change.
  7. How do antivirals work inside the body?
  8. Write two applications of monoclonal antibodies.
  9. Why can E. coli not produce human insulin directly?
  10. What is the difference between 25th percentile and 50th percentile?

Q4. Long questions (Attempt any 2 of 3 · 2 × 13 = 26)

  1. Describe lymphatic system of man.
  2. Compare monoclonal antibodies to other drug classes.
  3. Explain how biostatistics is applied in pollution indicators and environmental protection.