1st Year Biology Chapter 7 TestStructural and Computational Biology

Q1. Multiple choice questions (Attempt all · 10 × 1 = 10)

1. What is done after generating the density map?

   1. The crystal is melted

   2. Data is analyzed with computational tools

   3. The protein is frozen

   4. The protein is dyed

2. Why is 3D structure important for understanding function?

   1. It shows chemical reactions

   2. It reveals movement

   3. Shape determines how a molecule works

   4. It gives color to molecules

3. How does structural homology help understand evolution?

   1. By studying protein shapes and their conservation

   2. By comparing organism size

   3. By analyzing metabolic rates

   4. By sequencing RNA only

4. What does structural biology reveal about misfolding?

   1. Folding temperature

   2. Folding pathways and errors

   3. Protein color

   4. DNA sequences

5. Ligands in structural biology are:

   1. Membranes

   2. Hormones

   3. Molecules that bind to macromolecules

   4. Organs

6. FASTA is mainly used to search:

   1. Internet history

   2. Protein and nucleotide databases

   3. Computer errors

   4. Weather records

7. What causes diffraction of X-rays in a crystal?

   1. Electrons in a vacuum

   2. Magnetic fields

   3. Atoms in the crystal

   4. Water molecules

8. What role does computation play in X-ray crystallography?

   1. Produces radiation

   2. Analyzes diffraction data

   3. Grows crystals

   4. Filters proteins

9. Studying homologous genes in model organisms helps:

   1. Understand human diseases

   2. Create new species

   3. Reduce biodiversity

   4. Change gene sequences randornly

10. A drug target is usually:

    1. A DNA molecule

    2. A protein

    3. A carbohydrate

    4. A lipid