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Federal (FBISE) · Half book test (board pattern) · Free

2nd Year Chemistry Second half Book Paper

85 marks · 3 hours (Section A: 25 minutes) · 40 questions. Covers: 11 chapters (13. Polymers to 23. Industry).

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2nd Year Chemistry Second half Book Paper

2nd Year · Chemistry · Federal (FBISE)

Name: ____________Roll No: ________Class/Section: ________Date: ________Total marks: 85Time: 3 hours (Section A: 25 minutes)

Q1. Multiple choice questions (Attempt all · 17 × 1 = 17)

  1. Cosmetics are mixtures of:
    1. Organic compounds only
    2. Only hydrocarbons
    3. Minerals only
    4. Natural and synthetic chemicals
  2. Optimum temperature for human enzymes is about:
    1. 0°C
    2. 25°C
    3. 37°C
    4. 60°C
  3. Hydrolysis of condensed polymers can occur under:
    1. Neutral only
    2. Acidic or basic
    3. Enzymatic only
    4. High pressure only
  4. Which compound contributes to inflammation, pain, and fever?
    1. Prostaglandins
    2. Lipids
    3. Hormones
    4. Dopamine
  5. Spectroscopy is based on the interaction of atoms or molecules with:
    1. Heat
    2. Sound waves
    3. Electromagnetic radiations
    4. Chemical reactions
  6. Shorter retention times are associated with:
    1. Polar components with lower boiling points
    2. Non-polar components with high boiling points
    3. Metals
    4. Solvent molecules only
  7. Fertilizers increase the natural fertility of the soil or:
    1. Replace lost water
    2. Add pesticides
    3. Increase soil acidity
    4. Replace elements
  8. Two peaks in the chlorine mass spectrum show that:
    1. Chlorine has one isotope
    2. Chlorine has two isotopes
    3. Chlorine is monoisotopic
    4. Chlorine is a mixture with hydrogen
  9. The abundance of M+1 peak depends mainly on:
    1. Hydrogen atoms
    2. Oxygen atoms
    3. Carbon atoms
    4. Nitrogen atoms
  10. Which of the following is one of the strongest materials known?
    1. Silver
    2. Graphene
    3. Diamond
    4. Plastic
  11. Which database was used to screen molecules when discovering Halicin?
    1. PubChem
    2. DrugBank
    3. ZINC15
    4. ChemSpider
  12. Why can long-term use of opiates lead to addiction?
    1. Because they inhibit serotonin reuptake
    2. ecause they cause irreversible binding to receptors
    3. ecause they increase dopamine release in the brain
    4. Because they decrease the production of natural endorphins
  13. Fructose is classified as:
    1. Aldohexose
    2. Ketohexose
    3. Aldopentose
    4. Ketopentose
  14. Which of the following is a polyester?
    1. Kevlar
    2. Nylon-6,6
    3. Terylene
    4. PVC
  15. Which enzyme functions optimally in the acidic environment of the stomach?
    1. Amylase
    2. Trypsin
    3. Pepsin
    4. Lipase
  16. The property that makes nuclei NMR active is called:
    1. Isotopic mass
    2. Spin
    3. Charge density
    4. Energy difference
  17. The stationary phase in chromatography functions mainly as:
    1. A solvent
    2. An adsorbent
    3. A lubricant
    4. A catalyst

Q2. Short questions (Attempt any 7 of 10 · 7 × 3 = 21)

  1. Describe the process of virtual screening and its importance in the context of AI-driven drug discovery.
  2. Name the monomers of Nylon-6,6.
  3. What is the function of cellulose in plants?
  4. What is the effect of external magnetic field on the spinning nuclei?
  5. Why is scale important in drawn graphs?
  6. How is the relative abundance of isotopes determined in mass spectrometry?
  7. What is the function of virtual screening in drug development?
  8. Describe the chemical reaction between an amine and an acyl chloride to form an amide.
  9. Write function of RNA.
  10. What is deuterium exchange method and what is its use?

Q3. Short questions (Attempt any 7 of 10 · 7 × 3 = 21)

  1. Mention two examples of personal care products from the chemical industry.
  2. Give an example of an alloy and its components.
  3. Why should solvents not absorb UV light in UV detection methods?
  4. Describe the mechanism of action of penicillin.
  5. Name three macronutrients present in chemical fertilizers.
  6. What is clinkerization?
  7. Name four common examples of everyday materials.
  8. Give two applications of chromatography.
  9. Define the mechanism of drug action.
  10. List two benefits of using pesticides.

Q4. Long questions (Attempt any 2 of 3 · 2 × 13 = 26)

  1. Write a detailed note on how X-ray crystallography helps in understanding proteins, DNA, and RNA.
  2. Detail the classification of lipids and discuss their nutritional and biological importance.
  3. Examine the case study of Halicin to illustrate the broader implications of AI in drug repurposing. What were the key steps involved, and how did AI contribute to each step? What does this case study suggest about the future of AI in medicinal chemistry?