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Punjab (PTB) · Chapter test · Free

2nd Year Chemistry Chapter 9 TestORGANIC SYNTHESIS

30 marks · 40 minutes · 21 questions. Covers: CHAP 25: ORGANIC SYNTHESIS.

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2nd Year Chemistry Chapter 9 Test

2nd Year · Chemistry · Punjab (PTB)

Name: ____________Roll No: ________Class/Section: ________Date: ________Total marks: 30Time: 40 minutes

Q1. Multiple choice questions (Attempt all · 10 × 1 = 10)

  1. What was unique about the structure of the molecule picked out by the computer model?

    1. It was exactly identical to penicillin

    2. It lacked any functional groups or heteroatoms.

    3. It possessed a molecular structure different from existing antibiotics.

    4. It was an inorganic metal complex.

  2. How is a "disconnection" best described?

    1. A physical explosion in a laboratory flask

    2. An imaginary breaking down of bonds on paper

    3. The purification of an unreactive liquid

    4. The separation of a mixture using chromatography

  3. Beside acetophenone, what inorganic byproduct is generated during its forward synthesis?

    1. H2O

    2. NO2

    3. HCl

    4. H2SO4

  4. How many of the validated molecules from the database screening were described as "particularly powerful"?

    1. Two

    2. Eight

    3. Twenty-three

    4. All of them

  5. What is the molecule called whose synthesis is being planned or designed?

    1. Synthon

    2. Target Molecule (TM)

    3. Synthetic Equivalent (SE)

    4. Reagent

  6. What is the initial starting material (SM) used in the forward synthesis of Aspirin?

    1. Salicylic acid

    2. Acetic anhydride

    3. Phenol

    4. Acyl chloride

  7. Why can a synthon itself rarely be used directly in a laboratory reaction?

    1. It is far too expensive to purchase

    2. It is usually highly unstable or imaginary

    3. It turns into gas instantly at room temperature

    4. It does not dissolve in organic solvents

  8. When toluene is treated with KMnO4/H2SO4, we obtain:

    1. Benzyl chloride

    2. Benzenesulphonic acid

    3. Benzenecarboxylic acid

    4. Acetophenone

  9. What is a "Retrosynthetic Tree"?

    1. A taxonomic chart of organic plants

    2. A diagram showing all possible disconnections and paths

    3. A crystalline structure of solid organic compounds

    4. A sequence of forward combustion reactions

  10.  What is the chemical name or abbreviation given to the final desired drug molecule?

    1. SM

    2. SE

    3. Paracetamol (TM)

    4. FGI

Q2. Short questions (Attempt any 6 of 8 · 6 × 2 = 12)

  1. What is a "Target Molecule" (TM)?

  2. What target organism was chosen to train the machine-learning algorithm to recognize antibacterial traits?

  3. Highlight the efficiency of AI screening by comparing the size of the database to the time taken.

  4. Define organic synthesis.

  5. Identify the two synthetic equivalents chosen in Step II of the Aspirin scheme.

  6. Identify the catalyst and condition used to combine salicylic acid and acetic anhydride.

  7. Differentiate between synthesis and retrosynthesis.

  8. What is the full IUPAC or chemical alternative name provided for Aspirin?

Q3. Long questions (Attempt any 2 of 3 · 2 × 4 = 8)

  1. Give a detailed account of importance of retrosynthesis in organic synthesis.

  2. Elaborate on the Complete Retrosynthetic Analysis and Stepwise Forward Synthesis of Paracetamol.

  3. Design the synthesis of the following molecules starting from benzene.IMAGE