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Punjab (PTB) · Chapter test · Free

2nd Year Biology Chapter 11 TestPHARMACOLOGY

30 marks · 40 minutes · 21 questions. Covers: CHAP 23: PHARMACOLOGY.

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2nd Year Biology Chapter 11 Test

2nd Year · Biology · Punjab (PTB)

Name: ____________Roll No: ________Class/Section: ________Date: ________Total marks: 30Time: 40 minutes

Q1. Multiple choice questions (Attempt all · 10 × 1 = 10)

  1. Sulfonamides are often combined with which agent to create a stronger, bactericidal combined therapy?

    1. Quinine

    2. Trimethoprim

    3. Chloroquine

    4. Beta-lactamase

  2. To prevent reduced drug absorption, tetracycline should not be taken alongside:

    1. Water or juices

    2. Green leafy vegetables

    3. Dairy or iron supplements

    4. Carbohydrate-rich foods

  3. Penicillin primarily works to treat infections by inhibiting the synthesis of the bacterial:

    1. Cell wall

    2. Protein structure

    3. DNA replication sequence

    4. Folate metabolism path

  4. Fluoroquinolones are synthetic antibacterial agents derived as a byproduct of the synthesis of:

    1. Penicillin

    2. Tetracycline

    3. Chloroquine (quinine)

    4. Sulfanilamide

  5. Which group of authorities works alongside scientists to ensure new medicines are safe for public use?

    1. Regulatory authorities

    2. Financial planners

    3. Media outlets

    4. Environmental lawyers

  6. Monoclonal antibodies are considered highly affect because:

    1. Have broad spectrum action

    2. Are highly specific to antigens

    3. Do not bind to any target

    4. Are non-biological in nature

  7. Unlike penicillin, tetracycline does not kill bacteria outright but stops them from growing, meaning it has a:

    1. Bacteriostatic effect

    2. Bactericidical effect

    3. Lytic effect

    4. Mutagenic effect

  8. The drug discovery and development process begins with the identification of:

    1. Large manufacturing facilities

    2. Disease-causing targets

    3. Patient marketing strategies

    4. Chemical waste dump sites

  9. Penicillin inhibits bacterial cell wall synthesis by interrupting the cross-linking of:

    1. Peptidoglycan (murein) chains

    2. Cellulose fibers

    3. Lipopolysaccharide grids

    4. Aminoacyl-tRNA sites

  10. The ...... drugs are synthetic compounds derived from sulfanilamide:

    1. Penicillin

    2. Fluoroquinolones

    3. Sulfonamides

    4. Tetracycline

Q2. Short questions (Attempt any 6 of 8 · 6 × 2 = 12)

  1. Differentiate between the actions of Fluoroquinolones on Gram-positive versus Gram-negative bacteria.

  2. Define the primary purpose of drug discovery and drug development.

  3. Differentiate between in vitro and in vivo testing in Preclinical Research.

  4. What is meant by Target Identification?

  5. How does penicillin cause bacterial cells to burst (lysis)?

  6. Define Antibiotics.

  7. Describe the mechanism of action of Penicillin.

  8. Describe the step of Lead Compound Identification.

Q3. Long questions (Attempt any 2 of 3 · 2 × 4 = 8)

  1. Assess the possible consequences of the misuse and overuse of antibiotics on human health.

  2. Explain different type of antibiotics. Describe their mode of action.

  3. Describe the essential steps for the drug discovery and developmental process?