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Federal (FBISE) · Chapter test · Free

2nd Year Chemistry Chapter 14 Test14. Organic Synthesis

30 marks · 40 minutes · 21 questions. Covers: 14. Organic Synthesis.

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2nd Year Chemistry Chapter 14 Test

2nd Year · Chemistry · Federal (FBISE)

Name: ____________Roll No: ________Class/Section: ________Date: ________Total marks: 30Time: 40 minutes

Q1. Multiple choice questions (Attempt all · 10 × 1 = 10)

  1. Which database was used to screen molecules when discovering Halicin?
    1. PubChem
    2. DrugBank
    3. ZINC15
    4. ChemSpider
  2. What is the primary function of AI in drug discovery as exemplified by the discovery of Halicin?
    1. Manufacturing drugs
    2. Predicting biological activity and toxicity
    3. Performing virtual screening
    4. Both B and C
  3. What advantage does AI offer in the early stages of drug discovery?
    1. Increased manufacturing speed
    2. Reduction in the need for clinical trials
    3. Cost-effective narrowing down of potential candidates
    4. Ensuring drug approval from regulatory bodies
  4. Which database was used to screen molecules when discovering Halicin?
    1. PubChem
    2. DrugBank
    3. ZINC15
    4. ChemSpider
  5. AI narrowed the pool of possible drug candidates from:
    1. Thousands to hundreds
    2. Millions to a feasible size
    3. Billions to thousands
    4. Hundreds to tens
  6. AI reduces costs in drug development by:
    1. Increasing drug prices
    2. Narrowing down the list of potential candidates
    3. Extending experimental testing
    4. Eliminating clinical trials
  7. By minimizing the need for animal testing, AI contributes to:
    1. Increased drug cost
    2. Ethical drug discovery
    3. Longer approval time
    4. Delayed research
  8. Machine learning algorithms forecast the:
    1. Biological behavior and toxicity of substances
    2. Price of medicines
    3. Shelf-life of drugs
    4. Marketing demand
  9. Halicin was originally developed as a drug for:
    1. Cancer
    2. Diabetes
    3. Heart disease
    4. Hypertension
  10. Which advantage of AI in drug development relates to reducing the time needed to find new drug candidates?
    1. Cost-effectiveness
    2. Speed
    3. Innovation
    4. Accuracy

Q2. Short questions (Attempt any 6 of 8 · 6 × 2 = 12)

  1. Describe the process of virtual screening and its importance in the context of AI-driven drug discovery.
  2. What is the function of virtual screening in drug development?
  3. Explain how AI ensures cost-effectiveness in the drug discovery process.
  4. How did AI contribute to the discovery of Halicin?
  5. Which AI models are used for molecular generation?
  6. What role did the deep learning model play in the discovery of Halicin as an antibiotic?
  7. How did researchers confirm the effectiveness of Halicin as an antibiotic?
  8. What is meant by innovation as an advantage of AI in drug development?

Q3. Long questions (Attempt any 2 of 3 · 2 × 4 = 8)

  1. Examine the case study of Halicin to illustrate the broader implications of AI in drug repurposing. What were the key steps involved, and how did AI contribute to each step? What does this case study suggest about the future of AI in medicinal chemistry?
  2. Explain how artificial intelligence accelerates pharmaceutical research.
  3. Write a detailed note on the advantages of using AI in drug discovery and development.