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Federal (FBISE) · Chapter test · Free

2nd Year Chemistry Chapter 7 Test07. Organic Chemistry

30 marks · 40 minutes · 21 questions. Covers: 07. Organic Chemistry.

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2nd Year Chemistry Chapter 7 Test

2nd Year · Chemistry · Federal (FBISE)

Name: ____________Roll No: ________Class/Section: ________Date: ________Total marks: 30Time: 40 minutes

Q1. Multiple choice questions (Attempt all · 10 × 1 = 10)

  1. (+)-Ibuprofen is:
    1. Inactive
    2. Active
    3. Toxic
    4. Neutral
  2. Geometric isomerism is shown by
    1. alkenes
    2. alkynes
    3. alkanes
    4. lkanes
  3. Which one is the least stable compound?
    1. cis-but-2-ene
    2. rans-but-2-ene
    3. trans-hex-3-ene
    4. rans-pent-2-ene
  4. Asymmetric synthesis of (+)-thalidomide involves:
    1. Ordinary hydrogenation
    2. Use of chiral catalysts
    3. Free radical reactions
    4. Chain reactions
  5. The role of chiral catalyst in asymmetric synthesis is to:
    1. Stop hydrogenation
    2. Increase molecular weight
    3. Remove impurities
    4. Favor production of one enantiomer
  6. The (−)-enantiomer of thalidomide is:
    1. Sedative
    2. Harmless
    3. Teratogenic
    4. Pain reliever
  7. The (+)-enantiomer of thalidomide acts as:
    1. Teratogenic
    2. Sedative
    3. Analgesic
    4. Antipyretic
  8. A mixture containing equal amounts of two enantiomers is called:
    1. Isotonic mixture
    2. Geometric mixture
    3. Racemic mixture
    4. None
  9. Which isomerism is used to explain taste difference in amino acids?
    1. Chain isomerism
    2. Optical isomerism
    3. Geometric isomerism
    4. Structural isomerism
  10. Why is administration of a single enantiomer of thalidomide ineffective?
    1. They decompose quickly
    2. They interconvert in the body
    3. They are unstable in air
    4. They do not dissolve

Q2. Short questions (Attempt any 6 of 8 · 6 × 2 = 12)

  1. Define racemic mixture.
  2. How can a molecule be chiral yet remain optically inactive? Give the term used for such a molecule.
  3. What does “racemic mixture” mean?
  4. Why is it not effective to administer only the (+)-thalidomide enantiomer to patients?
  5. Draw the cis-trans isomers of hex-3-ene.
  6. Define chirality in relation to drug molecules.
  7. Why are cis-isomers polar while trans are non-polar?
  8. Why do alkanes not show geometric isomerism?

Q3. Long questions (Attempt any 2 of 3 · 2 × 4 = 8)

  1. Indicate which isomer would likely have a higher boiling point and why.
  2. Differentiate between cis-isomers and trans-isomers. Give examples with diagrams.
  3. Describe asymmetric synthesis of thalidomide and the role of chiral catalysts.