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2nd Year Chemistry Chapter 7 Test2nd Year · Chemistry · Federal (FBISE)
Q1. Multiple choice questions (Attempt all · 10 × 1 = 10)
- (+)-Ibuprofen is:
- Geometric isomerism is shown by
- Which one is the least stable compound?
- Asymmetric synthesis of (+)-thalidomide involves:
- The role of chiral catalyst in asymmetric synthesis is to:
- The (−)-enantiomer of thalidomide is:
- The (+)-enantiomer of thalidomide acts as:
- A mixture containing equal amounts of two enantiomers is called:
- Which isomerism is used to explain taste difference in amino acids?
- Why is administration of a single enantiomer of thalidomide ineffective?
Q2. Short questions (Attempt any 6 of 8 · 6 × 2 = 12)
- Define racemic mixture.
- How can a molecule be chiral yet remain optically inactive? Give the term used for such a molecule.
- What does “racemic mixture” mean?
- Why is it not effective to administer only the (+)-thalidomide enantiomer to patients?
- Draw the cis-trans isomers of hex-3-ene.
- Define chirality in relation to drug molecules.
- Why are cis-isomers polar while trans are non-polar?
- Why do alkanes not show geometric isomerism?
Q3. Long questions (Attempt any 2 of 3 · 2 × 4 = 8)
- Indicate which isomer would likely have a higher boiling point and why.
- Differentiate between cis-isomers and trans-isomers. Give examples with diagrams.
- Describe asymmetric synthesis of thalidomide and the role of chiral catalysts.